What is a key requirement in a containment facility regarding air pressure?

In a containment facility, maintaining positive air pressure is critical for preventing the escape of potentially harmful pathogens or contaminants into the surrounding environment. A positive air pressure ensures that air flows out of the facility when doors are opened, effectively minimizing the risk of airborne diseases spreading or contaminating other areas. This controlled environment is essential for the safety of both the animals housed within and any personnel working in proximity to them.

Additionally, while negative air pressure is commonly used in certain isolation facilities to contain hazardous materials or infections within a specific area, it does not apply broadly to typical containment facilities. Neutral air pressure would not provide any safety benefit in maintaining containment, and the idea that air pressure is irrelevant fails to recognize its critical role in biosafety and the protection of both animal and human health. Maintaining a positive pressure is therefore a key requirement in ensuring the containment facility's integrity and safety.