Which injection route requires ensuring you do not inject too much material into the muscle?

The intramuscular injection route is the correct choice because it involves administering substances directly into the muscle tissue. This method has a defined limit regarding the volume of material that can be safely injected. If too much liquid is injected into a muscle, it can lead to adverse effects, such as tissue damage, pain, or localized swelling. Each muscle group has its own maximum volume for injections, which is crucial to adhere to in order to avoid complications.

In contrast, intravenous injections deliver substances directly into the bloodstream, so the volume can be quite significant without the same risks associated with muscle tissue. Subcutaneous injections are administered just under the skin, where there tends to be more space for the injection, thus allowing for larger volumes relative to intramuscular injections but still with a risk of irritation if too much is given. Intraperitoneal injections are conducted within the peritoneal cavity, where larger volumes can generally be accommodated without the restrictions seen with intramuscular sites. Therefore, choosing the intramuscular route necessitates careful volume consideration to maintain animal welfare and prevent injury.